Emulsifying factors for dietary lipids, a prerequisite step for efficient lipid digestion. Facilitate intestinal lipid absorption by . This preview shows page 32 - 40 out of 40 pages.. Cholesterol Absorption Inhibitors #3 Cholesterol Absorption Inhibitors #3 Pharmacokinetics o Absorbed in the GI tract o Metabolized in the liver, excreted in urine and feces Contraindications o Allergy o Pregnancy or lactation if combined with a statin Winner of the Standing Ovation Award for “Best PowerPoint Templates” from Presentations Magazine. Serum cholesterol levels are determined by endogenous synthesis and intestinal absorption, which are differentially influenced by various classes of cholesterol-lowering agents. They include: soluble fibers, phytosterols, saponins, phospholipids, soy protein and stearic acid. At normal levels, it is an essential substance for the body. absorption) • Dosing & effect • 10 mg PO daily • Expect 15-25% ↓LDL-C Drug information: “Ezetimibe.” Drug Monograph. 2. Overview of lipid digestion 4. Graphic original. This is the reason that a high intake of fiber is recommended to decrease blood cholesterol. This is the reason that a high intake of fiber is recommended to decrease blood cholesterol. Composition different lipids in diet • Triglycerides (> 90%) • Cholesterol • Cholesteryl esters • Phospholipids, and • Unesterified fatty All of the above varieties of lipids are also synthesized in body 3. Overview of lipid digestion 5. Blocking absorption reduces the amount of cholesterol in chylomicrons, which eventually return to the liver with their cholesterol loads and contribute to VLDL production. Cofactor for pancreatic lipase and PLA2. … of cholesterol in bile. Cholesterol is both good and bad. cholesterol absorption • (Statins increase chol. PPT Cholesterol absorption (PPTX 1.6MB) Share this page with your colleagues and friends: Continue reading: 4 Things a cardiologist should know about triglycerides. They'll give your presentations a professional, memorable appearance - the kind of sophisticated look that today's audiences expect. Solubilizer. A number of different food components are known to reduce plasma and LDL-cholesterol levels by affecting intestinal cholesterol absorption. Gold Standard. Reducing triglycerides in REDUCE-IT 10' education - Feb. 11, 2020 - Prof. Deepak Bhatt, MD - Online CME. Cholesterol absorption is aided by an increase in dietary fat components and is hindered by high fiber content. Cholesterol absorption is aided by an increase in dietary fat components and is hindered by high fiber content. Background and objectives Recent clinical trials on cholesterol-lowering in patients with CKD yielded conflicting results, which might have resulted from different treatment strategies. 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